Ana içeriğe atla

Report: Covid-19 patients recovering quickly after getting experimental drug remdesivir

Report: Covid-19 Patients Recovering Quickly After Getting Experimental Drug Remdesivir


Covid-19 patients who are getting an experimental drug called remdesivir have been recovering quickly, with most going home in days, STAT News reported Thursday after it obtained a video of a conversation about the trial.
The patients taking part in a clinical trial of the drug have all had severe respiratory symptoms and fever, but were able to leave the hospital after less than a week of treatment, STAT quoted the doctor leading the trial as saying.
"The best news is that most of our patients have already been discharged, which is great. We've only had two patients perish," Dr. Kathleen Mullane, an infectious disease specialist at the University of Chicago who is leading the clinical trial, said in the video.
Mullane did not immediately respond to a request for comment from CNN.
The University of Chicago said Mullane's comments constituted partial information.
"Partial data from an ongoing clinical trial is by definition incomplete and should never be used to draw conclusions about the safety or efficacy of a potential treatment that is under investigation," it said in a statement.
"In this case, information from an internal forum for research colleagues concerning work in progress was released without authorization. Drawing any conclusions at this point is premature and scientifically unsound."
There is no approved therapy for the Covid-19, which can cause severe pneumonia and acute respiratory distress syndrome in some patients. But the National Institutes of Health is organizing trials of several drugs and other treatments, among them remdesivir.
The drug, made by Gilead Sciences, was tested against Ebola with little success, but multiple studies in animals showed the drug could both prevent and treat coronaviruses related to Covid-19, including SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome).
Back in February, the World Health Organization said remdesivir showed potential against Covid-19.
STAT said it obtained and viewed a copy of the video discussion Mullane had last week with colleagues about the trial.
"Most of our patients are severe and most of them are leaving at six days, so that tells us duration of therapy doesn't have to be 10 days," she was quoted as saying.
However, the trial does not include what's known as a control group, so it will be difficult to say whether the drug is truly helping patients recover better. With a control arm, some patients do not receive the drug being tested so that doctors can determine whether it's the drug that is really affecting their condition.
Trials of the drug are ongoing at dozens of other clinical centers, as well. Gilead is sponsoring tests of the drug in 2,400 patients with severe Covid-19 symptoms in 152 trial sites around the world. It's also testing the drug in 1,600 patients with moderate symptoms at 169 hospitals and clinics around the world.
Gilead said it expected results from the trial by the end of the month.
"We understand the urgent need for a COVID-19 treatment and the resulting interest in data on our investigational antiviral drug remdesivir," the company said in a statement to CNN. But it said a few stories about patients are just that -- stories.
"The totality of the data need to be analyzed in order to draw any conclusions from the trial. Anecdotal reports, while encouraging, do not provide the statistical power necessary to determine the safety and efficacy profile of remdesivir as a treatment for Covid-19," Gilead said.

Yorumlar

Bu blogdaki popüler yayınlar

Turkey: Scientist isolates SARS-CoV2 virus

Turkey: Scientist İsolates SARS-CoV2 virus Virologist at Ankara university successfully isolates coronavirus, first set in producing vaccine ANKARA   A Turkish virologist has successfully isolated SARS-COV-2, the novel coronavirus, in a bid to produce a vaccine against the deadly disease it causes which has claimed almost 68,000 lives across the globe. "Our university's Biotechnology Institute Director Prof. Dr. Aykut Ozkul succeeded in isolating the SARS-COV-2 virus, which is the first step of producing serum, vaccine, and medication against the coronavirus!" Ankara University said in a Twitter post. Mustafa Varank, Turkey's industry and technology minister, informed the public during the week that a total of 24 universities, eight public research and development units with hundreds of researchers have been working to produce a vaccine against COVID-19. On Sunday, Turkey announced the country's virus death toll climbed to 574 with 73 new d...

Going the distance to keep society safe - the coronavirus rules explained

Going the distance to keep society safe - the coronavirus rules explained Group of young adults practising social distancing. File image.  Credit: Klaus Vedfelt / Getty Images Coronavirus has forced people everywhere to make dramatic changes to their lives as governments work to try to drive the rate of infections down. From self-isolating to social distancing to when can you actually leave home - by law. Here, we explain some of the most important measures we’re all now being compelled to observe. What is social distancing? Firstly, it means keeping a physical distance between yourself and others. Secondly, it applies to the tough restrictions in place to stop people gathering in groups. How close can I get to others? The medical advice is you should keep 1.5 metres away from other people. No more handshakes, hugging or even air kisses. But chief medical officer Brendan Murphy has conceded families or people who live in the same house can hardl...

Coronavirus: What sporting events are affected by the pandemic?

Coronavirus: What sporting events are affected by the pandemic? As the virus spreads across the globe, sports bodies are cancelling or postponing events. The French Open has been postponed by four months and will now be played in September [File: Tim Clayton/Corbis/Getty Images] The 2020 Wimbledon tennis championships have been cancelled because of the coronavirus pandemic, the All England Club announced on Wednesday. It is the first time the championships, due to take place between June 28 and July 11, have been called off since World War II. The outbreak of the coronavirus, which has killed more than 47,000 people globally, has affected sporting events across the world. COVID-19, the disease caused by the novel coronavirus, has infected nearly 938,000 people worldwide. The International Olympic Committee and Japan's Prime Minister Shinzo Abe have postponed the  Tokyo  2020  Olympics, which will now take place from July 23...